St. Jude Discovers New Cure for Immunodeficiency Disorder

It’s hard to prevent your child from getting sick, but what happens when your child is unable to fight even the most common infections? SCID-XI is a chronic disorder that leaves children with little or no immune protection.

St. Jude Children’s Research Hospital has developed a new gene therapy that cures infants born with SCID-XI. With this new treatment, children were able to produce functioning immune cells for the first time. Prior to this, the best treatment for SCID-XI had been a bone marrow transplantation with a tissue-matched sibling donor, however more than 80% of SCID-XI patients lack such donors.

“These patients are responding to vaccinations and have immune systems to make all immune cells they need for protection from infections. This is a first for patients with SCID-XI,” said Dr. Eweline Mamcarz, of the St. Jude Department of Bone Marrow Transplantation and Cellular Therapy.

Read more about the new therapy here.